Basic Information
VIS ID
TVIS44005372
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47567019/47063762 (Hg38)
End
47567019/47063762 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/354408; hsa-let-7e/Downstream/163180;
Nearest TSS
ENST00000633603/Upstream/15132; ENST00000594526/Downstream/21593;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/14883, chr19-CpG: 20/Downstream/47389
Nearby gene
ZC3H4(-428) ;
Upstream sequence
tgagaggcgtgagccactgcgcccAAACTGtattgatcatgcattcagccatctatccacccatccttcatatttgttgatgcatttcaaagtaagttcc
Downstream sequence
aacatcaCAACAGACCCCTCCTCAGAGGATACCCCTGGCTATCACATGGGTAGGGTGCCTGCTAAAGCTCGTCCCGTCCCTGGAAGCCAGCCCAGCTGTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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