Basic Information
VIS ID
TVIS44005384
Fusion event
HTLV-1-ANAPC10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
145996841/145075689 (Hg38)
End
145996841/145075689 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANAPC10
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-12113/Upstream/1732154; hsa-mir-1305/Downstream/1332894;
Nearest TSS
ENST00000502981/Upstream/224117; ENST00000502586/Downstream/21693;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/429569, chr4-CpG: 59/Downstream/22322
Upstream sequence
taagctaggaaccgtgaatggggttgctgagcaccaggactcatttctggccctgagcagctcctggggaagaattaactaaataggtgtggagtagtcc
Downstream sequence
actctcaccatgtatctccagaattctagtggcaggaggccccacaacccccccaggcatctgaaccagcagggagtgctgcttggagagttagcaggca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate