Basic Information
VIS ID
TVIS44005401
Fusion event
HTLV-1-ATP1A4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
160122799/160153009 (Hg38)
End
160122799/160153009 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP1A4
Nearest miRNA
hsa-mir-101-1/Upstream/252930; hsa-mir-1182/Downstream/1074177;
Nearest TSS
ENST00000473358/Upstream/1423; ENST00000466526/Downstream/13519;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/53797, chr1-CpG: 61/Downstream/52291
Upstream sequence
tgtaatcccagctgcttgggaggctgaggcaggagaaacacctgttgggaggcagaggttgcagtgagtcgaaatcgcaccactgtacaccagcctgggc
Downstream sequence
aacagagtgactccatctcaaaaaaagaattgcagggagcttacaaaatggagcagtctcagtttggactaacaTTCTCCAGTCTGTTTCTCCCCCTCTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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