Basic Information
VIS ID
TVIS44005440
Fusion event
HTLV-1-SCAPER integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
77190958/76898617 (Hg38)
End
77190958/76898617 (Hg38)
Orient
-
Location type
Intronic
Target gene
SCAPER
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-10393/Upstream/1136302; hsa-mir-11181/Downstream/2311171;
Nearest TSS
ENST00000557528/Upstream/14741; ENST00000557805/Downstream/6662;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/551135, chr15-CpG: 77/Downstream/6300
Nearby gene
SCAPER(-14741) ;
Upstream sequence
taaaatgtggtatatccatatgatggaatattattcatccataaaaaggaatgaagggctgatatgtgctacaaaatggatgaatcttgaaaacattacg
Downstream sequence
ttaaatggaagaagccagacacaaaaggcttcgtactgtataattccatttatgtgaaatgtcctgaataggcaaatccataaagacagaaagtagatga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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