Basic Information
VIS ID
TVIS44005445
Fusion event
HTLV-1-ARSG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
66370666/68374525 (Hg38)
End
66370666/68374525 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARSG
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-10226/Upstream/902940; hsa-mir-1250/Downstream/49926;
Nearest TSS
ENST00000595228/Upstream/27380; ENST00000590690/Downstream/25631;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/82134, chr17-CpG: 70/Downstream/82683
Upstream sequence
TTACCTACTGATCTCCTATCTGAGGACTTGCCTTATTGATCTCTTCTCTCTTTATGAGGCAGTTTTGAAATAGTGAGTCAGGCTTAAGGATGTGGACTGG
Downstream sequence
GACCCCATTCTTCGAGGGAATGATGAGAAATACATTTACTAGCTggccaggtgcagtggctcatgcctgtagtcctagcactttgggaggctgaggcaag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate