Basic Information
VIS ID
TVIS44005480
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37/hg19
Start
35994383/36136865 (Hg38)
End
35994383/36136865 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/6179517; hsa-mir-10400/Downstream/5134183;
Nearest TSS
ENST00000518652/Upstream/41819; ENST00000522417/Downstream/642299;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/900272, chr8-CpG: 351/Downstream/1557561
Nearby gene
UNC5D(+342202) ;
Nearest cancer related gene
UNC5D(TSG, +342202) ;
Upstream sequence
TTAACTTTAAATTTATGTGTTATTAATCAGTGCTAGAACTATAAGGTGCTGAGTGAGTTACTGGGTGGGTCTCCACCATTTAAATACCTGTGTGGAAAAC
Downstream sequence
TTTATGCTTTCATTTGATGGAGAACATGACACAACCTAAGGCAAAATATTCTAATTGGAATTTTAAAAATATCCTTACTAGGAATTAAGTTTATACATCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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