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TVIS44005481
Basic Information
VIS ID
TVIS44005481
Fusion event
HTLV-1-AOPEP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
97544544/94782262 (Hg38)
End
97544544/94782262 (Hg38)
Orient
+
Location type
Intronic
Target gene
AOPEP
miRNAs that regulate target gene
hsa-mir-218-5p
;
hsa-mir-6820-5p
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-6087
;
hsa-mir-761
;
hsa-mir-3619-5p
;
hsa-mir-214-3p
;
hsa-mir-6510-5p
;
hsa-mir-6089
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
;
hsa-mir-518f-3p
;
hsa-mir-518c-3p
;
hsa-mir-518d-3p
;
hsa-mir-518b
;
hsa-mir-518a-3p
;
hsa-mir-6849-3p
;
hsa-mir-4293
;
hsa-mir-6771-3p
;
hsa-mir-3180-5p
;
hsa-mir-2355-5p
;
hsa-mir-1236-3p
;
hsa-mir-6893-3p
;
hsa-mir-370-3p
;
hsa-mir-4793-5p
;
hsa-mir-510-5p
;
hsa-mir-4786-5p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-640
;
hsa-mir-378a-5p
;
hsa-mir-1193
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-7107-5p
;
hsa-mir-1234-3p
;
hsa-mir-1224-3p
;
hsa-mir-2392
;
hsa-mir-1306-5p
;
hsa-mir-1343-3p
;
hsa-mir-23a-5p
;
hsa-mir-23b-5p
;
hsa-mir-4264
;
hsa-mir-4279
;
hsa-mir-4722-3p
;
hsa-mir-4740-3p
;
hsa-mir-498
;
hsa-mir-622
;
hsa-mir-660-3p
;
hsa-mir-6727-3p
;
hsa-mir-6742-3p
;
hsa-mir-6747-3p
;
hsa-mir-6783-3p
;
hsa-mir-6852-5p
;
hsa-mir-939-3p
Nearest miRNA
hsa-let-7a-1/Upstream/603342; hsa-mir-12126/Downstream/27700;
Nearest TSS
ENST00000422679/Upstream/21824;
ENST00000473778/Downstream/137953;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/55372
,
chr9-CpG: 164/Downstream/222105
Upstream sequence
ctgggcgacagagtgagactccgtctcaaaaaaaaaagaaacaaaaaaagaaaaaGAAAATACTCTGCTTCTGTTTTTTGTGGGAAGCCTCAAGTAAATG
Downstream sequence
AAGAAGACTGCCTAATGGAAGCTCCTTCCAGATGAAGGAGAAAAAGCATATGAACAAGTGAAAGGTGTTAAAAACTACATGTGCCCTTGCATAGGATCTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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