Basic Information
VIS ID
TVIS44005484
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
26811677/26485186 (Hg38)
End
26811677/26485186 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/578732; hsa-mir-101-1/Downstream/69356;
Nearest TSS
ENST00000473358/Upstream/11757; ENST00000525525/Downstream/44575;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/11835, chr1-CpG: 125/Downstream/14999
Nearby gene
HMGN2(+8544) ;
Upstream sequence
actctccaattactttccctaatataggcacctttcctgtcttggataaactatttgacaccttcaccttatctcccatcgctaacctgctttcttcacc
Downstream sequence
cacatcagcaatttcccttcatacttcatggtgatagaagatgtggtgagaaaagagctacctcgtcttcccaccacctcctctactacctacctgcagc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate