Basic Information
VIS ID
TVIS44005498
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
85951304/86240262 (Hg38)
End
85951304/86240262 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA11F
Nearest miRNA
hsa-mir-10392/Upstream/4349426; hsa-let-7a-2/Downstream/38071;
Nearest TSS
ENST00000527297/Upstream/46780; ENST00000533228/Downstream/4282;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/170907, chr11-CpG: 18/Downstream/4081
Nearby gene
EED(+4122) ;
Nearest cancer related gene
EED(TSG, +4122) ;
Upstream sequence
TATAAGTCTTATCAACAGGAGATACATGTTAATAGACTTGTCTTAAGAAGGTCTATAAGATCCTCcacgatctggccccttaccttcttttctagccttc
Downstream sequence
tctgttaccacacttttgtcaccttctcttttcagtccttcaccagcactgacctttcagtgtaccaatggcgtttgtactcttctcatattcctgcgcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate