Basic Information
VIS ID
TVIS44005506
Fusion event
HTLV-1-RXYLT1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
64209203/63815423 (Hg38)
End
64209203/63815423 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
RXYLT1-AS1
Nearest miRNA
hsa-let-7i/Upstream/1211654; hsa-mir-10527/Downstream/8240;
Nearest TSS
ENST00000382841/Upstream/10472; ENST00000542381/Downstream/6733;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/34965, chr12-CpG: 45/Downstream/6296
Upstream sequence
ccacgcctggctactttctgtattttttttttttcttagtagagataagggttttgccatgttggccaggctggtcttgaactcccgacctcaggtgatc
Downstream sequence
cacccacctcagcctcccaaaatgctaggattacaggcgtgagccaccgtgcccggtcTTGGGCCTAAATTTTTAAAACATTCCTTGTTTGCGTTTTTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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