Basic Information
VIS ID
TVIS44005534
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
38765971/40609719 (Hg38)
End
38765971/40609719 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/416056; hsa-mir-10226/Downstream/907445;
Nearest TSS
ENST00000595228/Upstream/44247; ENST00000619697/Downstream/22042;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/165665, chr17-CpG: 69/Downstream/37973
Nearby gene
SMARCE1(-18005) ;
Upstream sequence
acacaatgaagcctgtaacaGATAGGATGTTTTCTTTTCACATTTGTTCCATTACAAAACTACTCACTGTggccaggtgcagtggttcatgcctgtaatc
Downstream sequence
ccaacattttgggaggcagaggcaggaggattgcttgagcccaggaatttgagaccagcttgggcaacataggaagacccagtctgtacaaaaattaata
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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