Basic Information
VIS ID
TVIS44005536
Fusion event
HTLV-1-LOC105371843 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
56832737/58755376 (Hg38)
End
56832737/58755376 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371843
Nearest miRNA
hsa-mir-10226/Upstream/419354; hsa-mir-1250/Downstream/382382;
Nearest TSS
ENST00000595228/Upstream/8321; ENST00000308249/Downstream/493;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/62442, chr17-CpG: 98/Downstream/224
Nearby gene
PPM1E(+493) ;
Upstream sequence
TTTAAGAAATGAGAGTAACACCACTTTCTTCACAGAATCAAGTGAGAGAGAACCTATGCAAAGGAACTTATCACTTGGTAGGTATTTGAAGCTCCCTCTG
Downstream sequence
CCTGAAAACTACTTATTCAAAGACTGCAACAAAAGGTGTTCACAGTGTGGTATCTTTCAAAACATACGCTAAGGCAAGGAACAGATAAGGAAATGGAAGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate