Basic Information
VIS ID
TVIS44005537
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
67955563/69959422 (Hg38)
End
67955563/69959422 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/859766; hsa-mir-1250/Downstream/4789191;
Nearest TSS
ENST00000595228/Upstream/195745; ENST00000455460/Downstream/2285;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/631726, chr17-CpG: 87/Downstream/209350
Nearby gene
LINC01497(No orient, 2285)
Upstream sequence
ATTGAGAATGAAAAAGAAAGGAAAGAGATCTTGTGCAAGAATGGGCAGGGTGTTGTTTCAGATTACACCTGGAATAGAGTCAGAGTAACCAAAGATAAAT
Downstream sequence
CACATTTTAATTCCCAAGTGACACAACTTTTTGTCACAGTTCCTTGGAATTTCTACTGgagggttatatattatgatataacactttacacagtgcttgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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