Basic Information
VIS ID
TVIS44005546
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49279319/48776062 (Hg38)
End
49279319/48776062 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/1549041; hsa-let-7e/Downstream/233844;
Nearest TSS
ENST00000633603/Upstream/19975; ENST00000600406/Downstream/21481;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/22824, chr19-CpG: 28/Downstream/19086
Nearby gene
FGF21(+17737) ;
Upstream sequence
gtgtggtgctggaggcctctaatcctagctactcgggtggctgaggcaggagaatcgcttgaatccaggaggtggaggttgcagtgagccaagattatgc
Downstream sequence
cacttcactccagcctggacaacagagtgagactctgtctcaaaaaaataaataaataaagacaaattcaatacctctagttctctccctttccatattt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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