Basic Information
VIS ID
TVIS44005565
Fusion event
HTLV-1-IFT57 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
107897376/108178529 (Hg38)
End
107897376/108178529 (Hg38)
Orient
-
Location type
Intronic
Target gene
IFT57
Nearest miRNA
hsa-let-7g/Upstream/4654413; hsa-mir-12124/Downstream/1424299;
Nearest TSS
ENST00000440867/Upstream/11353; ENST00000462629/Downstream/41015;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/86833, chr3-CpG: 49/Downstream/43554
Upstream sequence
attttgagtatattaaagttaagtcactgtttatcataatacaaaaaggaaaaggacagctagagtagatatttgcagtacacatatctgacaagggatt
Downstream sequence
catatcctgaatatataaagaacttctataaatcaaaaggaaaagcagatggcccgatggctaaacacaaaagaagatatccaaaagctaaataagctta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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