Basic Information
VIS ID
TVIS44005593
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
90909006/91279691 (Hg38)
End
90909006/91279691 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7E
Nearest miRNA
hsa-mir-10525/Upstream/15364422; hsa-mir-10399/Downstream/924324;
Nearest TSS
ENST00000635602/Upstream/15327; ENST00000419226/Downstream/31677;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/12323, chr7-CpG: 35/Downstream/600992
Nearby gene
FZD1(+10874) ;
Upstream sequence
CTTCATTAGAGACAAACTGAATTAATGTAGGAGTTGTAGGGTGTGTTTGTAGACCTCAGATAAGACTGGTTACGATGGGGATATTTATTCAATGCTAACT
Downstream sequence
AAAATAAAATCAGATGATCTTCAAAATATACGGTATTTATCAGAGGTGACAATGGGTTACTAGGAAttcttaaaattgaatgtgcgtaaaaatcactcag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate