Basic Information
VIS ID
TVIS44005596
Fusion event
HTLV-1-EPHA1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q35
Reference genome
GRCh37/hg19
Start
143106560/143409467 (Hg38)
End
143106560/143409467 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
EPHA1-AS1
Nearest miRNA
hsa-mir-10399/Upstream/26667; hsa-mir-153-2/Downstream/3968550;
Nearest TSS
ENST00000635602/Upstream/575; ENST00000332690/Downstream/33986;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/27391, chr7-CpG: 73/Downstream/101425
Upstream sequence
GGTGTGACCTGGGTTTTCAGTGGCAGAGATTGGGAAAGGCACCAGCAAGGGCCTGAAGGCAGGGAGCCTCAAGGTGCGCCCAGGGAGTGGTGAATGGACC
Downstream sequence
AGTTTGACTGCTGGGGCGCAGGATTTGTCTTGGGAATCAGGGCAGAAAGGCAGGTGTGGGCCAGGGCTGGGTAAACAAGAAAAGGAGTTTGAACCTTGAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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