Basic Information
VIS ID
TVIS44005620
Fusion event
HTLV-1-MIR3681HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
12324427/12184301 (Hg38)
End
12324427/12184301 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR3681HG
Nearest miRNA
hsa-mir-4261/Upstream/347315; hsa-mir-10b/Downstream/14829;
Nearest TSS
ENST00000437798/Upstream/77717; ENST00000412606/Downstream/130016;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/399174, chr2-CpG: 204/Downstream/532198
Upstream sequence
TACTTAAGGCgggcatgttaattacatgctgagcttcaattatccgatctgtaaagtgaagaaaatgagactcttgaactcaagggttatCCTTGAAGAA
Downstream sequence
CACCTGATACAGTCCAGCTACAGTTTTCATTTCTCCAAATAATTCTGAAGGGTCTCGGGGTGCTGTGGATTTGCCTGATTTCTCTATGATTCGCTCCTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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