Basic Information
VIS ID
TVIS44005627
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1047946/997946 (Hg38)
End
1047946/997946 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3176/Upstream/227669; hsa-mir-11401/Downstream/737039;
Nearest TSS
ENST00000527434/Upstream/39; ENST00000564390/Downstream/2980;
Nearest CpG islands
chr16-CpG: 40/Target, None/Upstream, None/Downstream
Nearby gene
SOX8(+10967) ;
Upstream sequence
TGGGGTCTGGAGGCCTCACCCCACCCCCGCCTCCCGCTCCACACGCCCGCCTGTGAGGTTCGGGGCGCGGCTCCCCTGGGGAGGGCTCCCTGTCACCTGT
Downstream sequence
TCCTCCCATCTGAGAGCTCGCCAGAGGACTGTGGGTGGCAGCGGGTGCGGCAGATCCGGCGTGTGGGCGCCGACTGCTCCTGCCTCACTGCCACGGTGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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