Basic Information
VIS ID
TVIS44005681
Fusion event
HTLV-1-TMEM272 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
52399295/51825159 (Hg38)
End
52399295/51825159 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
TMEM272
Nearest miRNA
hsa-mir-15a/Upstream/272492; hsa-mir-1267/Downstream/984891;
Nearest TSS
ENST00000623511/Upstream/20862; ENST00000242819/Downstream/19991;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/20722, chr13-CpG: 118/Downstream/186019
Upstream sequence
taagcagggcatgcctaacatcttgtgaactcttcttggaagaacagagccatataataagtgttaatttttgaattgcactgtaataatcacagcacca
Downstream sequence
gggcctgctgaagtgattgaattgttcactcttacactaaatggccccagactacttggctgtttcagttctctgcaaaccttaaaatcttatcttcttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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