Basic Information
VIS ID
TVIS44005693
Fusion event
HTLV-1-LOC102724948 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
20738444/20538684 (Hg38)
End
20738444/20538684 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102724948
Nearest miRNA
hsa-mir-3125/Upstream/1190179; hsa-mir-10b/Downstream/4789956;
Nearest TSS
ENST00000437798/Upstream/37373; ENST00000272224/Downstream/48002;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/90457, chr2-CpG: 56/Downstream/112268
Nearby gene
HS1BP3-IT1(No orient, 52091)
Upstream sequence
TGGTGGCACCAGCCCATGCACCTGCTCACCCTTGAGCAGGAGCACGTCTTTGACCCCAGGAAGAACAGGAGGCAGGAGAGACTGTCCCCAGGGTGGGAGC
Downstream sequence
TTTCCTGATGGTGGCTGCAGGGACCCCCTGGGCACAGAAGCCAACAGTGATGGTGGCCTGATCAGCTTGTGTTGCTCGGCCTCTGCCCCTGAGCTGGGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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