Basic Information
VIS ID
TVIS44005704
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
1535422/1533695 (Hg38)
End
1535422/1533695 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-571/Upstream/1183443; hsa-mir-12113/Downstream/452689;
Nearest TSS
ENST00000502981/Upstream/127364; ENST00000608161/Downstream/16589;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/435, chr4-CpG: 26/Downstream/3355
Nearby gene
FAM53A(-106186) ;
Upstream sequence
ACAGAGATCCATCAGCCTTCCCACAATTAACGCCGAATCGCCACCCTCACCTCCTAAATTACACCGGCGGCCGCAGCCAGCCCGGACCAGCGTAAATCAC
Downstream sequence
GTTCTGACTGCCGCGCGTCAGGGCAGAGGCTCTCCCGCTGAGAGCAGTGTTACTGTCTCCTAAATCCCAAAGCCATGATTGATGCCACCTGCTCCACACG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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