Basic Information
VIS ID
TVIS44005709
Fusion event
HTLV-1-NUP155 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
End
37321961/37321859 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-let-7b-5p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-let-7e-5p ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-298 ; hsa-mir-219b-3p ; hsa-mir-4795-5p ; hsa-mir-6840-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-302f ; hsa-mir-4536-5p ; hsa-mir-944 ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-4738-3p ; hsa-mir-1244 ; hsa-mir-624-5p ; hsa-mir-4500 ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-let-7a-5p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-1294 ; hsa-mir-4316 ; hsa-mir-638 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-1273g-3p ; hsa-mir-4257 ; hsa-mir-561-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-9-5p ; hsa-mir-4267 ; hsa-mir-378a-5p ; hsa-mir-4312 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-1273d ; hsa-mir-4677-3p ; hsa-mir-4793-3p ; hsa-mir-548s ; hsa-mir-649 ; hsa-mir-7703
Nearest miRNA
hsa-mir-10397/Upstream/1173871; hsa-mir-103a-1/Downstream/1235643;
Upstream sequence
ACACAAAGTATGAATAATGTTATATAAAAGTGTACTTACTTAGACTCTGTTTTTGCTTTTAAAGAAGTGTATATTTATGTATGCTTTATTATTTATTTAT
Downstream sequence
GATAtttttttttgagacagagtttcactcttgttgcccaggctggagtgcaatggcacgatctgggctcaccgcaacctccgcctcccaggtttaagtg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate