Basic Information
VIS ID
TVIS44005711
Fusion event
HTLV-1-LOC101928573 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
20299591/20299360 (Hg38)
End
20299591/20299360 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101928573
Nearest miRNA
hsa-mir-3691/Upstream/1727480; hsa-mir-10398/Downstream/6848266;
Nearest TSS
ENST00000381078/Upstream/86961; ENST00000613242/Downstream/102546;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/86458, chr6-CpG: 177/Downstream/102126
Nearby gene
MBOAT1(-86896) ;
Upstream sequence
TTATGAGGAACTGGATGAGCCAGAAGAGTTGCCCAGGTCAACACTGGACCCTGGCTTGCAGTTGAGTGCAGGAAAGAGAGAACTGTTGGTAATATCATGA
Downstream sequence
AGCTACAATCACattaaatattttatttaggccgggagcagtggctcacgcctgtaatcccagcactttgggaggccgaggcgggcggatcatgaggtca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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