Basic Information
VIS ID
TVIS44005729
Fusion event
HTLV-1-TEKT4P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
13309955/11154279 (Hg38)
End
13309955/11154279 (Hg38)
Orient
+
Location type
Intronic
Target gene
TEKT4P1
Nearest miRNA
hsa-mir-3690-2/Upstream/6548051; hsa-mir-12120/Downstream/2324898;
Nearest TSS
ENST00000430575/Upstream/1243481; ENST00000417071/Downstream/1508055;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/46219, chrY-CpG: 30/Downstream/14649
Upstream sequence
AAGACGCCATGAAAGGATCCCACCAGGAAAGTGGCTCTAGGGCAGAGCATAAATTACTAGGGTCCTCCCAGGGAGCGCGGGCCTGAGTGGGAATGAGTGA
Downstream sequence
CCCGCGTGCAATCTCGACCCTGGCAGGACAGGACTGGCCTCAGCCGACCAGGCTCAGTTCTTTCCGTTCCTGATATTTGACGGAAGGAGGCACCCAGTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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