Basic Information
VIS ID
TVIS44005730
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
14432421/12311694 (Hg38)
End
14432421/12311694 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/7705466; hsa-mir-12120/Downstream/1167483;
Nearest TSS
ENST00000430575/Upstream/2400896; ENST00000417071/Downstream/350640;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/324920, chrY-CpG: 122/Downstream/108622
Nearby gene
LOC106128902(+501) ;
Upstream sequence
tcacattaattaatgcatgtaatcctcatagcttctctgtaaagtagacactggttttcctcattttacacatgaagaaaccaaatcacagGAACATCTC
Downstream sequence
CATGATGATATtggaacaggaattaaaagaaattaaagagtgtgtaagcaaaaactcagttgtttgtaggaaaacccaatttcccctgaggaagagaaag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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