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TVIS44005742
Basic Information
VIS ID
TVIS44005742
Fusion event
HTLV-1-HSD17B12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
43768902/43747352 (Hg38)
End
43768902/43747352 (Hg38)
Orient
-
Location type
Intronic
Target gene
HSD17B12
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-874-3p
;
hsa-mir-191-5p
;
hsa-mir-381-3p
;
hsa-mir-6811-5p
;
hsa-mir-6511b-5p
;
hsa-mir-4771
;
hsa-mir-1205
;
hsa-mir-1972
;
hsa-mir-4494
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-3714
;
hsa-mir-548an
;
hsa-mir-633
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-510-3p
;
hsa-mir-222-5p
;
hsa-mir-142-3p
;
hsa-mir-494-3p
;
hsa-mir-29a-5p
;
hsa-mir-3129-5p
;
hsa-mir-199b-3p
;
hsa-mir-199a-3p
;
hsa-mir-936
;
hsa-mir-205-3p
;
hsa-mir-4280
;
hsa-mir-3163
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-450b-5p
;
hsa-mir-527
;
hsa-mir-518a-5p
;
hsa-mir-548aw
;
hsa-mir-1288-5p
;
hsa-mir-382-3p
;
hsa-mir-4284
;
hsa-mir-4772-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-1304-3p
;
hsa-mir-6741-3p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-5698
;
hsa-mir-744-3p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-675-5p
;
hsa-mir-4466
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-103b
;
hsa-mir-7705
;
hsa-mir-7703
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-542-3p
;
hsa-mir-5186
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-6849-3p
;
hsa-mir-598-5p
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-1273a
;
hsa-mir-6501-3p
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-24-3p
;
hsa-mir-383-3p
;
hsa-mir-3614-5p
;
hsa-mir-1227-3p
;
hsa-mir-3160-3p
;
hsa-mir-1247-3p
;
hsa-mir-340-3p
;
hsa-mir-3689d
;
hsa-mir-4537
;
hsa-mir-455-3p
;
hsa-mir-4684-5p
;
hsa-mir-548c-3p
;
hsa-mir-6134
;
hsa-mir-6499-3p
;
hsa-mir-6516-5p
;
hsa-mir-6771-3p
;
hsa-mir-6807-5p
;
hsa-mir-6827-3p
;
hsa-mir-6851-5p
;
hsa-mir-6880-5p
;
hsa-mir-7847-3p
;
hsa-mir-129-5p
;
hsa-mir-2113
;
hsa-mir-371b-5p
;
hsa-mir-373-5p
;
hsa-mir-4474-3p
;
hsa-mir-4698
;
hsa-mir-5010-3p
;
hsa-mir-5692a
;
hsa-mir-616-5p
;
hsa-mir-7108-5p
;
hsa-mir-8063
Nearest miRNA
hsa-mir-129-2/Upstream/165869; hsa-let-7a-2/Downstream/1944352;
Nearest TSS
ENST00000527297/Upstream/23313;
ENST00000532178/Downstream/6692;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/66305
,
chr11-CpG: 27/Downstream/133352
Upstream sequence
GGAAATACAATTCAAAATAGAGTGGTAAAGTGCCATAGACTTAAAGATGTGCCAAGTGTTGTGGGAGTTTAGAAAGAGGAAGTTTTCTTTCACGTAAAGT
Downstream sequence
GATCTAGAACAGTGAAGTTGGTGGATCTTCAATAAGGCTTTGATGGAAGAGGGTAGGAGGTGAGGTTCTGtgttggaaacagggcttgtggggtgcctgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL48
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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