Basic Information
VIS ID
TVIS44005767
Fusion event
HTLV-1-LOC102723560 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
62849505/62815601 (Hg38)
End
62849505/62815601 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102723560
Nearest miRNA
hsa-mir-1225/Upstream/5043249; hsa-mir-11401/Downstream/4386720;
Nearest TSS
ENST00000527434/Upstream/219229; ENST00000561595/Downstream/553243;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/778871, chr16-CpG: 19/Downstream/2135177
Upstream sequence
GGTTTTAACTTATGAGAGAGTTCACACTAAGACAAAATAATTTTAGTAAGGAAGAAATAGATCCTGTAATTGGATGAAATGTGTGGGGGAGATAATTTCA
Downstream sequence
TTTCAAGAGTTAGTTATTTTAGCTCTTTTTGGGAGGTAAGGTAGGTTTGGGAAGATATCCAATTGGATTCACTTGATTCAGTAATATCTAACTCTGTATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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