Basic Information
VIS ID
TVIS44005770
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
90011810/89945402 (Hg38)
End
90011810/89945402 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-11401/Upstream/1229065;
Nearest TSS
ENST00000527434/Upstream/22036; ENST00000564836/Downstream/2523;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/9554, chr16-CpG: 29/Downstream/2440
Nearby gene
DEF8(+3329) ;
Upstream sequence
ggaggctgaggtgggcagatcacttgagctcaggagttggagaccagcctgggcaacatggcaagaccctgtctctataaaaaatacaaaaattagctgg
Downstream sequence
gcatggtggtgcatgcctgtggtcccaggtacttggcctgaggcgggaggatcatttgagcccaggagatggaggcCAGTCTGGGCAACCCCATCTGAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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