Basic Information
VIS ID
TVIS44005807
Fusion event
HTLV-1-LOC102467217 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
114980586/115644889 (Hg38)
End
114980586/115644889 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LOC102467217
Nearest miRNA
hsa-mir-10397/Upstream/5130974; hsa-mir-103a-1/Downstream/610854;
Nearest TSS
ENST00000502646/Upstream/11897; ENST00000512900/Downstream/47278;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/18617, chr5-CpG: 122/Downstream/170762
Upstream sequence
CTCCACTATTCCCATCTCTTTCACCTGAATCCCACCTTTACTTTTCTCCTTTCACAAAGGCAAAGACTTTGATGCTGGGGGTAAAAAGAAGAGAACCCGC
Downstream sequence
AACCCCTAGCTGCCTCATCCTCCCCACCCATAGGCCATTCAGCTGTGTCTGAGGCATCTTCTCGTTTCCCCAACAGCCTGCTTGCCAAATCCCCAAGCCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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