Basic Information
VIS ID
TVIS44005846
Fusion event
HTLV-1-MIR548AI integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
30091411/29622205 (Hg38)
End
30091411/29622205 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR548AI
Nearest miRNA
hsa-mir-208a/Upstream/1988927; hsa-mir-1185-1/Downstream/1392441;
Nearest TSS
ENST00000550708/Upstream/24537; ENST00000550941/Downstream/12269;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/836342, chr14-CpG: 147/Downstream/304799
Upstream sequence
cataaggagtgcacaaccagaagatccttctcttgtgcagttcacaatagggtttgcactcctatgacaatctaatgctgctgctgttcttaaggaggcg
Downstream sequence
gaacacagaagataatgctttctggcccaccgcacacctcctgttgttcggcccagttcctaacaggccacgtacaggtacaggtccacggcctggggac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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