Basic Information
VIS ID
TVIS44005865
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
GRCh37/hg19
Start
24456342/24438225 (Hg38)
End
24456342/24438225 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-23c/Upstream/4421038; hsa-let-7f-2/Downstream/4057330;
Nearest TSS
ENST00000429181/Upstream/265469; ENST00000493226/Downstream/26996;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/75676, chrX-CpG: 103/Downstream/26674
Nearby gene
PDK3(+27002) ;
Upstream sequence
TGAAACCCCCATCTGAGAACAGTGCTCTATAGACTGGAACTGAGAGCGTAGGTAGGGTAGTTGATTTGCATTTGTGTTGCTAATCAAGAAGTTTTAAGAA
Downstream sequence
CAATTATGGAACATTTTTGAAAAACACAGCTAAACAATACCTGGAAAATTAAGCAAAAACAATAATTACAGTGTTTATTGCTATCTTAGTTCTGTACGAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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