VISDB Viral Integration Site DataBase

VIS ID

TVIS44005879

Fusion event

HTLV-1-PRICKLE1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

q12

Reference genome

Start

End

42886621/42492819 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-17-5p ; hsa-mir-455-3p ; hsa-mir-340-5p ; hsa-mir-2355-5p ; hsa-mir-6818-5p ; hsa-mir-147a ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-92b-5p ; hsa-mir-581 ; hsa-mir-6780b-3p ; hsa-mir-488-5p ; hsa-mir-6831-3p ; hsa-mir-4732-3p ; hsa-mir-6732-3p ; hsa-mir-6771-3p ; hsa-mir-6514-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-5693 ; hsa-mir-665 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-4325 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4793-3p ; hsa-mir-4799-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4704-3p ; hsa-mir-551b-5p ; hsa-mir-4668-3p ; hsa-mir-6516-5p ; hsa-mir-203b-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-5186 ; hsa-mir-1247-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/168960; hsa-let-7i/Downstream/4694993;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/8428, chr12-CpG: 107/Downstream/96506

Nearest cancer related gene

PRICKLE1(TSG, No orient, 0)

Upstream sequence

TTTTGATCCAAGTTACTTTTAATATTTATTTTCTCCTTTATGTTTGGAGAGCTTTAATCTCTTGAACATTGAGTCTGCGCTGGATTATAGAGGGACTagg

Downstream sequence

gaagggatcttgtctgttttgtttaatgatatatccaaagtgctgagatactctggcctggtacatTAGATACAGCAGATACTTTACCTGGCATCTAGGG