Basic Information
VIS ID
TVIS44005884
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
17297091/17393777 (Hg38)
End
17297091/17393777 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1253/Upstream/1111689; hsa-mir-10226/Downstream/419703;
Nearest TSS
ENST00000595228/Upstream/48508; ENST00000585041/Downstream/83209;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9719, chr17-CpG: 23/Downstream/83084
Nearby gene
NT5M(+46114) ;
Upstream sequence
tggactcccgcctagcgataaagtgagactccgtctcaaaacaaaaaacaaacgaaaacaaCAGTGACAACAAAACACACAAAAGACAAGCCAACAGAAT
Downstream sequence
AACATCACTGGTCCTCAGACAGGTGGATGATTGGATAGGCAGGTGATAAGGAGGTAGGTAAGCAGGGCTTACCTGAAGCTCATGGAGCGGAAGTTCAATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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