Basic Information
VIS ID
TVIS44005895
Fusion event
HTLV-1-FGF2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.1
Reference genome
End
123749335/122828180 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-140-5p ; hsa-mir-503-5p ; hsa-mir-155-5p ; hsa-mir-186-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-103a-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-15b-5p ; hsa-mir-562 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-5697 ; hsa-mir-15a-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-450a-1-3p ; hsa-mir-497-5p ; hsa-mir-1276 ; hsa-mir-2278 ; hsa-mir-3148 ; hsa-mir-4668-5p ; hsa-mir-4670-3p ; hsa-mir-451b ; hsa-mir-6838-5p ; hsa-mir-181c-3p ; hsa-mir-25-3p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-495-3p ; hsa-mir-92b-3p ; hsa-mir-548c-3p ; hsa-mir-5688 ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-600 ; hsa-mir-646 ; hsa-mir-545-3p ; hsa-mir-1468-3p ; hsa-mir-548p ; hsa-mir-6504-3p ; hsa-mir-107 ; hsa-mir-3686 ; hsa-mir-222-5p ; hsa-mir-506-5p ; hsa-mir-936 ; hsa-mir-5695 ; hsa-mir-892c-5p ; hsa-mir-152-3p ; hsa-mir-5589-3p ; hsa-mir-759 ; hsa-mir-5003-3p ; hsa-mir-708-3p ; hsa-mir-4291 ; hsa-mir-3691-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-6853-3p ; hsa-mir-1206 ; hsa-mir-582-5p ; hsa-mir-3529-3p ; hsa-mir-627-3p ; hsa-mir-302a-5p ; hsa-mir-466 ; hsa-mir-1284 ; hsa-mir-4729 ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-6074 ; hsa-mir-26b-3p ; hsa-mir-3129-5p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-3935 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-577 ; hsa-mir-7109-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-3607-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-196a-3p ; hsa-mir-132-3p ; hsa-mir-205-3p ; hsa-mir-152-5p ; hsa-mir-203a-3p ; hsa-mir-195-3p
Nearest miRNA
hsa-mir-12113/Upstream/8171326; hsa-mir-1305/Downstream/2679079;
Nearest CpG islands
Upstream sequence
atattactaccttgcagcaggcttgaggatgaaatgagaattgcaGTTTTGCTTTCTGTAAGAAACAATGTTTGTGGTTCTAGAAAGAACACTGGCCTAA
Downstream sequence
ATAAGGAGTGCTTGGACTTTAGGGgattccctaagtctggagtgggggctgaagatttgcatttctaacatgttccccggggatgctgatcacatcacac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate