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TVIS44005895
Basic Information
VIS ID
TVIS44005895
Fusion event
HTLV-1-FGF2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.1
Reference genome
GRCh37/hg19
Start
123749335/122828180 (Hg38)
End
123749335/122828180 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGF2
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-140-5p
;
hsa-mir-503-5p
;
hsa-mir-155-5p
;
hsa-mir-186-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-103a-3p
;
hsa-mir-32-5p
;
hsa-mir-92a-3p
;
hsa-mir-15b-5p
;
hsa-mir-562
;
hsa-mir-4524a-5p
;
hsa-mir-4524b-5p
;
hsa-mir-5697
;
hsa-mir-15a-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-450a-1-3p
;
hsa-mir-497-5p
;
hsa-mir-1276
;
hsa-mir-2278
;
hsa-mir-3148
;
hsa-mir-4668-5p
;
hsa-mir-4670-3p
;
hsa-mir-451b
;
hsa-mir-6838-5p
;
hsa-mir-181c-3p
;
hsa-mir-25-3p
;
hsa-mir-7-1-3p
;
hsa-mir-7-2-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-495-3p
;
hsa-mir-92b-3p
;
hsa-mir-548c-3p
;
hsa-mir-5688
;
hsa-mir-101-3p
;
hsa-mir-144-3p
;
hsa-mir-600
;
hsa-mir-646
;
hsa-mir-545-3p
;
hsa-mir-1468-3p
;
hsa-mir-548p
;
hsa-mir-6504-3p
;
hsa-mir-107
;
hsa-mir-3686
;
hsa-mir-222-5p
;
hsa-mir-506-5p
;
hsa-mir-936
;
hsa-mir-5695
;
hsa-mir-892c-5p
;
hsa-mir-152-3p
;
hsa-mir-5589-3p
;
hsa-mir-759
;
hsa-mir-5003-3p
;
hsa-mir-708-3p
;
hsa-mir-4291
;
hsa-mir-3691-3p
;
hsa-mir-7157-5p
;
hsa-mir-4310
;
hsa-mir-376b-3p
;
hsa-mir-376a-3p
;
hsa-mir-6853-3p
;
hsa-mir-1206
;
hsa-mir-582-5p
;
hsa-mir-3529-3p
;
hsa-mir-627-3p
;
hsa-mir-302a-5p
;
hsa-mir-466
;
hsa-mir-1284
;
hsa-mir-4729
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-6074
;
hsa-mir-26b-3p
;
hsa-mir-3129-5p
;
hsa-mir-199a-3p
;
hsa-mir-199b-3p
;
hsa-mir-3935
;
hsa-mir-6831-5p
;
hsa-mir-3927-3p
;
hsa-mir-577
;
hsa-mir-7109-3p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-3607-3p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-6739-5p
;
hsa-mir-6733-5p
;
hsa-mir-3153
;
hsa-mir-1305
;
hsa-mir-607
;
hsa-mir-3671
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-196a-3p
;
hsa-mir-132-3p
;
hsa-mir-205-3p
;
hsa-mir-152-5p
;
hsa-mir-203a-3p
;
hsa-mir-195-3p
Nearest miRNA
hsa-mir-12113/Upstream/8171326; hsa-mir-1305/Downstream/2679079;
Nearest TSS
ENST00000502981/Upstream/1349;
ENST00000422835/Downstream/56532;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/355
,
chr4-CpG: 48/Downstream/94027
Upstream sequence
atattactaccttgcagcaggcttgaggatgaaatgagaattgcaGTTTTGCTTTCTGTAAGAAACAATGTTTGTGGTTCTAGAAAGAACACTGGCCTAA
Downstream sequence
ATAAGGAGTGCTTGGACTTTAGGGgattccctaagtctggagtgggggctgaagatttgcatttctaacatgttccccggggatgctgatcacatcacac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL220
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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