Basic Information
VIS ID
TVIS44005906
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
33439556/33421439 (Hg38)
End
33439556/33421439 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-23c/Upstream/779880; hsa-let-7f-2/Downstream/4602456;
Nearest TSS
ENST00000429181/Upstream/81998; ENST00000445233/Downstream/305069;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2154537, chrX-CpG: 36/Downstream/304874
Nearby gene
DMD(-81830) ;
Nearest cancer related gene
DMD(TSG, -81830) ;
Upstream sequence
agtggcagatgttggcatggatgtggggaaaagggacacttacacactgttggtgggaatgtaaattgaaacaatctctatggaaaacagtatggagatt
Downstream sequence
cctcaaagaaccaaaaatagaactactattggatccagcaatcctactactggatatatttccaaaggaaacaaaatgtttatatctaaaagacatctgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate