VISDB Viral Integration Site DataBase

VIS ID

TVIS44005919

Fusion event

HTLV-1-ZNF439 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.2

Reference genome

Start

End

11964067/11853252 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-376a-3p ; hsa-mir-376b-3p ; hsa-mir-181d-5p ; hsa-mir-4262 ; hsa-mir-4480 ; hsa-mir-4701-5p ; hsa-mir-3691-3p ; hsa-mir-500b-3p ; hsa-mir-3922-5p ; hsa-mir-4753-5p ; hsa-mir-1264 ; hsa-mir-302e ; hsa-mir-1304-5p ; hsa-mir-6765-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-526b-5p ; hsa-mir-5581-3p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-2467-5p ; hsa-mir-485-5p ; hsa-mir-3975 ; hsa-mir-6872-3p ; hsa-mir-586 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6809-3p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-6873-3p ; hsa-mir-6845-3p ; hsa-mir-329-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-5001-3p ; hsa-mir-638 ; hsa-mir-4713-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-6741-3p ; hsa-mir-6894-3p ; hsa-mir-378a-5p ; hsa-mir-4763-5p ; hsa-mir-6778-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-6747-3p ; hsa-mir-3653-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p

Nearest miRNA

hsa-mir-1181/Upstream/357630; hsa-let-7e/Downstream/850349;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/4003, chr19-CpG: 34/Downstream/34737

Nearby gene

ZNF439(+12777) ;

Upstream sequence

ctcttgacctcgtgatccacctgccttggactctcaaaagtgctgggattacaggtgtgagccaccacgcctggcctaaattagtaattttcaagagttg

Downstream sequence

tatttcaatttgatttCAGGGTCGTTAGGtaccacggaccctactggattgaacaaaggaggacgaatgcgggaataaagacaaaggcaaaagaatatgt