Basic Information
VIS ID
TVIS44005935
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
106133622/105685747 (Hg38)
End
106133622/105685747 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6F
Nearest miRNA
hsa-mir-10398/Upstream/6561051; hsa-mir-1202/Downstream/1098378;
Nearest TSS
ENST00000381078/Upstream/53551; ENST00000424894/Downstream/207294;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/282365, chr6-CpG: 57/Downstream/295489
Nearby gene
PREP(-282623) ;
Upstream sequence
cttgaattgtagttcccataatccccatgtgtcgtggaagggacctcttgagaggtaagtgaatcatgggggcagttaccccatgctgttctcatgatag
Downstream sequence
tgagtgagttctcacaagatctggtggtttcataaggggctttgcccctttgctcggcactcattctctctcctgccaccttgtgaaggagtgccttctg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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