Basic Information
VIS ID
TVIS44005942
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
2845997/2845883 (Hg38)
End
2845997/2845883 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/1137015; hsa-mir-10397/Downstream/3981970;
Nearest TSS
ENST00000502646/Upstream/10744; ENST00000515086/Downstream/119123;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/88973, chr5-CpG: 23/Downstream/20702
Nearby gene
C5orf38(No orient, 90486)
Upstream sequence
GTTCCCATGGGGTTGGCATGAAATGTAAAAAGGGAAATTGGGAGAGCGTCCACATAAAGGTGCGGTGGGTGTCATCTTCCTAAGAATAACATCAGAGATA
Downstream sequence
GAAACCACAAAAGACTAATAGAGCAGATTAAAGAAAACCAACAGAAAATGGTCCTCCAGTATTTGTAGCGGTcaataagaaatactggagagagagagaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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