Basic Information
VIS ID
TVIS44005953
Fusion event
HTLV-1-ATP1A1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
116957989/116415367 (Hg38)
End
116957989/116415367 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ATP1A1-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/3533238; hsa-mir-1182/Downstream/144657;
Nearest TSS
ENST00000473358/Upstream/9258; ENST00000624685/Downstream/18001;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/41176, chr1-CpG: 44/Downstream/3193
Upstream sequence
gcatggtactgttggtggcagagttaagccactgtattaaccaccttggggcctgcatcacctctagtcttccctttaagtgagataataaatgtcctcc
Downstream sequence
tcatctaagttagattgagccaggatttctgacacttgcagTGAGAAGGATATGGACAGATGCAGCCTCTAAGCCAGGGGTTTTTGAATCTTTTTTTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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