Basic Information
VIS ID
TVIS44005964
Fusion event
HTLV-1-LOC105369743 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
45895870/45502087 (Hg38)
End
45895870/45502087 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369743
Nearest miRNA
hsa-mir-1244-3/Upstream/3178228; hsa-let-7i/Downstream/1685725;
Nearest TSS
ENST00000382841/Upstream/166538; ENST00000427628/Downstream/108503;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/285118, chr12-CpG: 72/Downstream/224856
Nearby gene
ANO6(+61683) ;
Upstream sequence
TATTCAAAGATGAGGACTCCACGGCAGAACTATTTAGAGGCTATGATTTTTTCGCTCTAATATATCACATTTCTGGTTGATGTAAATGACACTTTAAAAT
Downstream sequence
GAGAAACATACTATATTTATATCTTACTGGTAGTGAAAAATTAGCTTTCATATGCTCCAGATGCTATTTGATACACATCTGTCTGCCTACGCTCCATGTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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