Basic Information
VIS ID
TVIS44005974
Fusion event
HTLV-1-LOC728755 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
27881355/27412149 (Hg38)
End
27881355/27412149 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC728755
Nearest miRNA
hsa-mir-208a/Upstream/503424; hsa-mir-1185-1/Downstream/221056;
Nearest TSS
ENST00000550708/Upstream/538986; ENST00000555350/Downstream/200439;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1206877, chr14-CpG: 203/Downstream/1353534
Nearby gene
LINC00645(No orient, 200439)
Upstream sequence
AAATGACTTCACTGAATAAATACCTTTGCTACATGCTTCAGGCTTTGTTTTAGTTTTTGTTTGTTTCTTTACCAAGCTATTTTTGAACACTTTTAAGTAA
Downstream sequence
TAGTCTTATCAACTAAAGTAACAGCTTAAACATTTATAGTTTATTTTAATGTATATATTGATAAAAATATATCAATTTAGATGATATCAAATATGTCAAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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