Basic Information
VIS ID
TVIS44005987
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
121387453/120629877 (Hg38)
End
121387453/120629877 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/6908509; hsa-mir-10b/Downstream/6793660;
Nearest TSS
ENST00000437798/Upstream/71768; ENST00000418323/Downstream/80588;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/42112, chr2-CpG: 28/Downstream/24530
Nearby gene
LINC01101(No orient, 163528)
Upstream sequence
TTGAGAGCTCCCCAGTCTGCTCTCGGGGCCCAGACAACAGCCTCTGAGCCTCCCCTCTGGTGATGAAGGCTTTGTCTCTTAGTAAGAAAGCATAAGCGAG
Downstream sequence
GAGCCTGGGGTGGGTTTCTGAAAGGGCCCCTCCTTCTCCACTGCTGGCTTGAGGTCTCCCCACAGTGGGGGTTTCTGAGCCCTAGGCAGTGCTCTGTGTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate