Basic Information
VIS ID
TVIS44005993
Fusion event
HTLV-1-DGCR5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
18997305/19009792 (Hg38)
End
18997305/19009792 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
DGCR5
Nearest miRNA
hsa-mir-3198-1/Upstream/1028831; hsa-let-7a-3/Downstream/953961;
Nearest TSS
ENST00000624155/Upstream/50280; ENST00000609630/Downstream/8042;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/11605, chr22-CpG: 150/Downstream/19508
Upstream sequence
ttttctcaaggctttaggggagaatctgtttccttgccttttccagcttatagaggcagccatgttttttggcttgtggccccttcctccatcttcaaag
Downstream sequence
ccaacagctggtcaagttgtcacattgcgtcactctgaccataggttatctgcttttaaggtcttgtgtgatttgattgggtccacctggaccattcagg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate