Basic Information
VIS ID
TVIS44006015
Fusion event
HTLV-1-LOC107986620 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
85115401/84405683 (Hg38)
End
85115401/84405683 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986620
Nearest miRNA
hsa-mir-10398/Upstream/5866374; hsa-mir-1202/Downstream/5907059;
Nearest TSS
ENST00000381078/Upstream/178048; ENST00000591225/Downstream/65221;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/177673, chr6-CpG: 129/Downstream/357301
Nearby gene
LINC01611(No orient, 15350)
Upstream sequence
ACATACATATGTATATGGTTATGTATATACTTACTGCTGGGTCCTTCCTAGAATTTGCTCACAAATGGTAGAGTTTTGTTCAGTATTGGTAGAATATACC
Downstream sequence
CAGCATACAAAAATAAAGATGTGACACTAATTTATTTAGAAACATGTTTCTAAGATTATAAAGTCACATTTTTCTCAATTGGCTTCATTACTTTGATCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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