Basic Information
VIS ID
TVIS44006048
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
233842712/233706966 (Hg38)
End
233842712/233706966 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/82747; hsa-mir-1537/Downstream/599501;
Nearest TSS
ENST00000473358/Upstream/51271; ENST00000366617/Downstream/197967;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/92162, chr1-CpG: 118/Downstream/197741
Nearby gene
KCNK1(+34454) ;
Upstream sequence
TAGTCTTAAATCCATCGTTGGGATGAAGGGCAAGtatattagtccattttcacactgctataaaggaataccagagactgagtaatttataaaggaaaca
Downstream sequence
ggtttcattgactcacagttccacatggctgaggaggcctcaggaaacttacaatcacagcggaaagggaagcaggcaccttcttcacatagcagcagga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate