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Viral Integration Site DataBase
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TVIS44006062
Basic Information
VIS ID
TVIS44006062
Fusion event
HTLV-1-CAPRIN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
34107933/34086386 (Hg38)
End
34107933/34086386 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA11E
Target gene
CAPRIN1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-34a-5p
;
hsa-mir-21-5p
;
hsa-mir-1296-5p
;
hsa-mir-92b-3p
;
hsa-mir-484
;
hsa-mir-222-3p
;
hsa-mir-92a-3p
;
hsa-mir-3678-3p
;
hsa-mir-2467-3p
;
hsa-mir-223-3p
;
hsa-mir-6868-3p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-589-3p
;
hsa-mir-548c-3p
;
hsa-mir-587
;
hsa-mir-3117-3p
;
hsa-mir-1197
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6509-5p
;
hsa-mir-4677-5p
;
hsa-mir-6844
;
hsa-mir-6873-3p
;
hsa-mir-6867-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-331-5p
;
hsa-mir-22-5p
;
hsa-mir-2116-5p
;
hsa-mir-567
;
hsa-mir-942-5p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-6832-3p
;
hsa-mir-4469
;
hsa-mir-4678
;
hsa-mir-452-3p
;
hsa-mir-6777-3p
;
hsa-mir-483-3p
;
hsa-mir-6715a-3p
;
hsa-mir-141-5p
;
hsa-mir-497-3p
;
hsa-mir-33b-5p
;
hsa-mir-33a-5p
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-4317
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4694-3p
;
hsa-mir-1-5p
;
hsa-mir-129-5p
;
hsa-mir-2113
;
hsa-mir-5010-3p
;
hsa-mir-758-3p
Nearest miRNA
hsa-mir-210/Upstream/5608838; hsa-let-7a-2/Downstream/855451;
Nearest TSS
ENST00000527297/Upstream/30648;
ENST00000528948/Downstream/3640;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/33230
,
chr11-CpG: 60/Downstream/18895
Upstream sequence
TCCTAACTTAACCTGTAGGATTCAATGCTGGATTTTGAAAATCAGACACTTGATCCTGCCATTGTATCTGCACAGCCTATGAATCCAACACAAAACATGG
Downstream sequence
ACATGCCCCAGCTGGTTTGCCCTCCAGGTTAGTAGTGGTACATTTTTATGTGAGAGAGAAATATAAGGCCAGTACTTTCAGGTTTTAAAAAGATTGTGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL103
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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