Basic Information
VIS ID
TVIS44006068
Fusion event
HTLV-1-LOC105369617 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
5386937/5277771 (Hg38)
End
5386937/5277771 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369617
Nearest miRNA
hsa-mir-3649/Upstream/3617391; hsa-let-7i/Downstream/1685928;
Nearest TSS
ENST00000382841/Upstream/34620; ENST00000544842/Downstream/12709;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/134367, chr12-CpG: 56/Downstream/152958
Upstream sequence
tgtgtgtacatgtgtgCAGCAGGTGTTTGTGGATATAAACACTATATGTGTATGTGTATTTTATATGTAGAGAGAAAGAGACAGAGAATATAATAAGTCC
Downstream sequence
TGTTTAATGGTTATAAACAAAACGTTATGAAGTGTTTTAAAGCAACAAGAAGTTGGAAATCCAGGAGGTCTGCATGGTGGAGAGGGCATTTACACATGGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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