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TVIS44006078
Basic Information
VIS ID
TVIS44006078
Fusion event
HTLV-1-RNASEH2B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51537044/50962908 (Hg38)
End
51537044/50962908 (Hg38)
Orient
+
Location type
Intronic
Target gene
RNASEH2B
miRNAs that regulate target gene
hsa-mir-328-3p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-561-5p
;
hsa-mir-6778-5p
;
hsa-mir-1233-5p
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6878-5p
;
hsa-mir-766-5p
;
hsa-mir-6077
;
hsa-mir-4708-3p
;
hsa-mir-4481
;
hsa-mir-4745-5p
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-7703
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-542-3p
;
hsa-mir-661
;
hsa-mir-4252
;
hsa-mir-2277-3p
;
hsa-mir-6776-5p
;
hsa-mir-4793-3p
;
hsa-mir-3605-3p
;
hsa-mir-766-3p
;
hsa-mir-6742-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-665
;
hsa-mir-6771-5p
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-6787-3p
;
hsa-mir-6746-5p
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-216b-5p
;
hsa-mir-216a-5p
;
hsa-mir-34b-3p
Nearest miRNA
hsa-mir-15a/Upstream/913707; hsa-mir-1267/Downstream/385659;
Nearest TSS
ENST00000623511/Upstream/14844;
ENST00000614264/Downstream/148301;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/52453
,
chr13-CpG: 86/Downstream/259073
Upstream sequence
ctttttgtttatctcatttgggagtgtattaagctccttgaacttttgagtttttaattttcatcaaatatggaaaatttctggccaatatttctttaaa
Downstream sequence
tacctttttccattctttcctcccttttctccctatcccctcagcttctggcctccaatttcatgtatgctggaacacttggtattgtcctccaggtcct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL103
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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