Basic Information
VIS ID
TVIS44006104
Fusion event
HTLV-1-LOC105371356 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
79723385/79689488 (Hg38)
End
79723385/79689488 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16D
Target gene
LOC105371356
Nearest miRNA
hsa-mir-1225/Upstream/2820469; hsa-mir-11401/Downstream/1695530;
Nearest TSS
ENST00000527434/Upstream/13380; ENST00000561510/Downstream/24359;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/87848, chr16-CpG: 42/Downstream/851356
Nearby gene
MAFTRR(No orient, 31824)
Upstream sequence
aaaaatagtgacaacaccaaaaggtagtgagcatgcagagaaactggatcactgacacatttctggtgggaatgtaacgcggccatgccattctgaaaag
Downstream sequence
cagtctggcaatttcttatacaattaactatgtaattgtcatatgaccgcaccattattctctgggatatttatcccagaaaaatgaaaatatatgttta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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